Hair Transplant for Treatment of Psoriasis

Psoriasis is an autoimmune disease with skin presentations in different parts of the body. We have noted improvement in psoriasis skin manifestation in a patient with long standing psoriatic lesions of the scalp. We actively sought additional patients with scalp psoriasis and transplanted hair into their scalp into, or in close proximity, of psoriatic lesions in order to elicit a response. Method: We transplanted hair into the psoriatic lesions of three patients after having confirmed the clinical diagnosis with pathology from the psoriatic lesions. We observed the lesions after the hair transplant and evaluated them clinically and histologically for continued evidence of active psoriasis. Results: We have documented clearance of the scalp psoriatic lesions in all three patients after one hair transplant procedure. All three patients were evaluated periodically within 7 to 15 months after their hair transplant. They underwent a repeat biopsy from the area of the original psoriatic plaque. The pathologic findings were consistent with post-operative changes. No histologic evidence of psoriasis was documented in any of the three patients. One of the 3 patients has been followed for five plus years and exhibits no evidence of disease recurrence. Conclusion: We suggest that transplantation of hair follicular units into psoriatic scalp lesions could be an effective method to alleviate the symptoms of psoriasis and possibly be used as a treatment option. More studies on the exact mechanism of this phenomenon may lead the way to novel treatments for this chronic disorder. Hair Transplant for Treatment of Psoriasis Case Report Advances in Plastic & Reconstructive Surgery © All rights are reserved by Parsa Mohebi. useful characterization of serotonin receptor subtypes in the treatment of ISSN: 2572-6684